Procaine HCl CAS 51-05-8

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Procaine HCL, also known by its former trade name Novocaine, is a synthetic ester-type local anesthetic used to block pain by preventing nerve cells from transmitting electrical signals. It is administered via injection for procedures like dental work, nerve blocks, and spinal anesthesia.

Product name	Procaine Hydrochioride
CAS No.	51-05-8
Molecular formula	C13H21ClN2O2
Molecular weight	272.77
EINECS number	200-077-2
Melting point	155-156°C(Predicted)
Storage condition	Refrigerator
Purity	>99%
Standard	Pharmaceutical Grade
Appearance	White or almost white crystal powder

The difference between Procaine hcl and Procaine base

Feature	Procaine Base	Procaine Hydrochloride
Solubility	Poorly soluble in water; lipid-soluble.	Highly soluble in water, making it suitable for injectable solutions.
Chemical Stability	Less stable in aqueous solutions than the salt form.	More chemically stable, allowing for longer storage.
Activity in the Body	This is the active form that diffuses through the fatty membranes of nerve cells to block sodium channels.	The ionized form is the transport molecule. It must be converted into the base form to enter the nerve cell.
Medical Use	Not used directly in injections due to poor water solubility. However, it is used in “procaine-base infusions” in combination with an alkalizing agent.	The standard injectable form for local anesthesia, nerve blocks, and dental procedures.